ADRESA PROFESIONALA:
Institutul National de Cercetare Dezvoltare pentru Stiinte Biologice Bucuresti, Splaiul Independentei nr. 296, sector 6, 060031, Bucuresti, Romania, POB 17-16
Tel/Fax: (40) 21 220 08 81;
Secretariat Tel/Fax: (40) 21 220 77 80; (40) 21 220 76 95
E-mail: a.rugina@yahoo.com
STUDII:
Universitatea din Bucuresti, Facultatea de Biologie, Diploma de licenta in Biologie, 1992
GRADE ACADEMICE:
Licentiat in Biologie - 1992
Doctor in Biologie - 2009
STAGII DE SPECIALIZARE SI CERCETARE:
1992 - prezent - asistent cercetare, cercetator stiintific, cercetator stiintific gr. III, la Institutul National de Cercetare-Dezvoltare pentru Stiinte Biologice, Bucuresti
VIIIeme Ecole D’ete Francophone: "Biologie et pathologie moléculaires. Biotechnologies", sous les auspices de l'Universite "Al. I. Cuza" de Iasi, de l'Ambassade de France en Roumanie et du Ministere de l'Enseignement Superieur et de la recherche (Iasi, 3-15 iulie, 2000)
XVIeme Ecole D’ete Francophone : « PATHOLOGIE ET PHARMACOLOGIE MOLECULAIRES BIOTECHNOLOGIES », sous les auspices de l'UniversiteVasile Goldis Arad, de l'Ambassade de France en Roumanie et du Ministere de l'Enseignement Superieur et de la recherche (Arad, 7-19 iulie, 2008
DOMENII DE COMPETENTA SI CERCETARE STIINTIFICA:
studii privind obtinerea inhibitorului acrozinic si implicatiile acestuia in procesul fertilizarii; corelatii intre actiunea unor hormoni steroizi si inhibitori proteazici asupra activitatii acrozinice
experimente de imobilizare ale inhibitorilor serin proteazici
obtinerea de extracte vegetale
studii de citometrie in flux asupra viabilitatii celulare a spermatozoizilor
ACTIVITATE STIINTIFICA:
12 articole stiintifice publicate in reviste de specialitate
36 comunicari si lucrari publicate in rezumat in volumele unor congrese, conferinte si simpozioane nationale si internationale
2 cereri de brevet de inventie
1 brevet de inventie (Nr. RO 122233 B1 / 27.02.2009) « Metoda de determinare cantitativa a sulfatului de protamina imobilizat pe support de natura proteica »
Director de proiect la 2 contracte (Program Nucleu, GRANT) si participant la realizarea de contracte de cercetare castigate prin competitie in cadrul PNCDI I, CEEX si PNCDI II
MEMBRU AL ASOCIATIILOR PROFESIONALE:
Societatea Romane de Biochimie si Biologie Moleculara (afiliata Federatiei de Societati Europene de Biochimie (FEBS)
Societatea Romana de Biologie Celulara
Societatea Romana de Biochimie si Biologie Moleculara (RSBMB)
Societatea Romana de Citometrie
LUCRARI STIINTIFICE REPREZENTATIVE:
Eugenia Teodor, Alexandrina Rugina, Wanda Buzgariu, Mirela Diaconu, G.L. Radu, „Protease inhibition and antioxidant actionns of some aqueous Allium extracts”, Innovations in Chemical Biology, Cap. 41, p 472-479, ISBN: 978-1-4020-6954-3, Editura Springer (2009)
Eugenia Teodor, Alexandrina Rugina, G. L. Radu, “Hydrogel-biomaterials based on polysaccharides for biomedical applications”, Revista de Chimie, 56, 12, 1211-14. (2005)
Rugina A., Takacs L, Iordachel C., Caloianu M., Bratosin D., “Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors”, Studia Universitatis “Vasile Goldis” Arad, Seria Stiintele Vietii, Vol. 18, p 187-195; ISSN: 1584-2363 (2008)
Rugina Alexandrina, Luminita Tcacenco, Maria Caloianu, “Collagenous substrate to determine acrosinic activity”, Romanian Journal of Biological Sciences, III (4), 57-61 (1999)
Alexandrina Rugina, Luminita Tcacenco, Maria Caloianu: “Collagenous film for qualitative determination of acrosinic activity”, First National Symposium of Biomaterials-present and future, Piatra Neamt, 30-31 august, 2000, PROGRESE IN STIINTA BIOMATERIALELOR, p. 100-102 ISBN 973-8149-09-6
Luminita Tcacenco, Rugina Alexandrina, Eugenia Teodor, Affin support bsa-protamine immobilized to heparin izolation from solutions, Rom. Biol. Sciences, 1(3-4) 31-36 (2004)
Alexandrina Rugina, Luminita Tcacenco, Maria Caloianu, «Quick method for determining the activity acrozinice », International Symposium: New technology in detergents, cosmetics and auxiliaries, Bucuresti, 24-25 octombrie, Rezumatul Comunicarilor Stiintifice p. 22, (2001)
Eugenia Teodor, Alexandrina Rugina, Mirela Diaconu, G. L. Radu, „Hydrogels biomaterials based on chitosan and hyaluronic acid”, Al V-lea Simpozion National de Biomateriale, Iasi, 28-29 oct. vol. rez. p. 117 (2005)
Alexandrina Rugina, Eugenia Teodor, Luminita Tcacenco, G. L. Radu, „Serin protease inhibitors immobilization supports in the form of membrane hyaluronic acid-chitosan », A XXIII-a Annual Scientific Session of the Society of Cell Biology June 9-12 Sibiu, volume summaries, p.253, (2005)
Alexandrina Rugina „Actiunea spermicidica a inhibitorilor proteazici din cateva extracte apoase vegetale (genul Allium)” al III-lea Workshop "Bioanaliza versus Biotehnologia", Bioanaliza Center, National Institute of R & D for Biological Sciences, Bucharest, October 6 - Oral Presentation (2006)
Eugenia Teodor, Alexandrina Rugina, Maria Caloianu, Radu G.L. „Spermicidal-Protease Inhuibition Action Of Some Medicinal Plants Extracts (Allium)” The 2nd International Congress of Cellular and Molecular Biology” „The 24th Annual Session of the Romanian Society for Cell Biology” Iasi 7-10 june, Abstract Book, p 62 (2006)
Alexandrina Rugina Eugenia Teodor, Mirela Diaconu, G.L.Radu „Protease inhibition and antioxidant action of some aqueous Allium extracts” 9th Eurasia Conference on Chemical Sciences (euAs C2S-9) septmber 9-13, Antalya Turkey, Abstracts, p156 (2006)
Alexandrina Rugina, Eugenia Teodor, Mirela Diaconu, Laura Stefan, G.L.Radu „Aqueous Allium extracts with antioxidant and protease inhibition properties” al IV-lea Simpozion cu perticipare internationala „Drug research between information and life sciences” Bucuresti 19-20 octobre, Abstract Book, p 85, (2006)
Rugina Alexandrina, Buia-Takacs L., Caloianu M., Bratosin D., “Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors”, International workshop "From basic science to Therapeutic Application", Bucuresti, Romania; 6-10 iunie, Bucuresti, Romania, (2007)
Rugina Alexandrina, Buia-Takacs Luminita, M.Caloianu, Bratosin D., “Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors”, Third National Congress of Citometrie, 9-11 May, Bucuresti, Romania, (2007)
Alexandrina Rugina, Luminita Takacs, Maria Caloianu, Daniela Bratosin „Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors” Third National Congress of Citometrie 9-11 mai 2007, Bucuresti, Volumul de Rezumate, p. 49-50 (si prezentare orala)(2007)
Alexandrina Rugina, Luminita Takacs, Maria Caloianu, Daniela Bratosin „Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors” A XXVe Session Annual Scientific Society of Cell Biology June 7-9, Bucharest, Volume Summaries p.65, (2007)
Alexandrina Rugina, Ana-Maria Gheorghe, C. Iordachel, Maria Caloianu, Daniela Bratosin „Noi metode de determinare a acrozinei/proacrozinei active din sperma utilizand ca substrat (CBZ-ALA-ARG) 2-R-110 si inhibitor de tripsina ALEXA FLUOR 488 Conjugat prin citometrie in flux” A XXVI-a Annual Scientific Session of the National Society for Cell Biology, 12-15 iunie, Cluj-Napoca, Volumul de Rezumate p. 187, (2008)
Alexandrina Rugina, Eugenia Teodor, Ana Maria Gheorghe „Study on immobilization of some extracts of vegetable origin on supports in the forms of chitosan-peg membranes and microparticles” International Conference “Biomaterials & Medical devices” BioMed’ 2008, 7rd General Meeting of Romanian Society for Biomaterials, Bucharest, 13-16th November (2008)
Alexandrina Rugina, Luminita Takacs, Maria Caloianu, Daniela Bratosin „Characterization by conventional flow cytometric parameters and apoptotic markers of the he-goat sperm under the action of acrosinic natural inhibitors” BioMed’ 2008, 7rd General Meeting of Romanian Society for Biomaterials, Bucharest, 13-16th November (2008)
Alexandrina Rugina, Ana-Maria Gheorghe, Catalin Iordachel, Maria Caloianu, Daniela Bratosin, Novel flow cytometric methods for determination of activable proacrosin / acrosin in sperm using (CBZ-Ala-Arg)2-R-110 substrate and Alexa Fluor® 488 conjugate trypsin inhibitor from soybean, The fourth national congress citometrie,Predeal,07-10 mai, (2008)
Romana | 
English
