Publicatii

LUCRARI STIINTIFICE PUBLICATE IN REVISTE DE SPECIALITATE COTATE ISI / INDEXATE IN BAZE DE DATE INTERNATIONALE

1. Elena I. Oprita, Lucia Moldovan, Oana Craciunescu, Wanda Buzgariu, Christu Tardei, Otilia Zarnescu, 2006, A bioactive collagen-β tricalcium phosphate scaffold for tissue engineering, Central European Journal of Biology, 4(1):61-72

CARTI/CAPITOLE PUBLICATE

1. Elena Iulia Oprita, Valentina Alexandru, G.L.Radu, Lucia Moldovan, Capitolul III - Caracterizarea componentei celulare a implanturilor osoase utilizate in ingineria tisulara in Tehnici Experimentale in Bioanaliza, Vol 4, 98-126, 2006.

COMUNICARI PREZENTATE LA CONFERINTE NATIONALE

1. Craciunescu Oana, Stefan M. Laura, Coroiu Viorica, Moldovan Lucia, Testarea in vitro a efectului radioprotector al unor amestecuri de colagen cu ceai verde, Workshop Bioanaliza, oct 2006, Bucuresti.
2. Buiculescu R., Extractia compusilor biologic activi din spanz si efectul lor asupra celulelor, Sesiunea de comunicari stiintifice studentesti 2006, Universitatea Politehnica din Bucuresti.
   

COMUNICARI PREZENTATE LA CONFERINTE INTERNATIONALE

1. Oana Craciunescu, Wanda Buzgariu, Viorica Coroiu, Laura Stefan, Manuela Mateescu, Iulia Oprita, Lucia Moldovan, In vitro radioprotective effect of a collagen-green tea mixture conditioned as gel, 2006, The 4th Conference on Medicinal and Aromatic Plants of South-East European Countries - Book of Abstracts, Iasi, Alma Mater Publishing House, 97.
2. Lucia Moldovan, Oana Craciunescu, Maria Lungu, Traian Leau, Otilia Zarnescu, Comparative study of tissue response after subcutaneous implantation of collagen-GAG sponges and collagen-PVC composites for medical use, 2006, The 5th International Congress of Pathophysiology, Beijing, China, Chinese Journal of Pathophysiology, 22 (13), Suppl., 516.
3. V. Alexandru, V. Coroiu, E.I. Oprita, E.Gille, L.Moldovan. Investigating medicinal plants for wound healing with the use of cell culture technologies.Poster and abstract. Proceeding of the 4th Conference on Medicinal and Aromatic Plants of South – East European Countries, Iasi, 28 – 31 May, 2006.
4. Elena I. Oprita, Lucia Moldovan, Oana Craciunescu, Otilia Zarnescu, 2006, In Vitro Evaluation of a Microporous Collagen – β Tricalcium Phosphate Composite for Bone Repair, The International Conference “Biomaterials in Regenerative Medicine”, Viena, Book of Abstracts, 63.
5. A. Stoleriu, M.C. Popescu, L. Moldovan, O. Craciunescu, C. Vasile, 2006, Effect of molecular structure on the molecular mobility of elastin, International Conference on Biomaterials and Medical Devices BIOMMED, Abstract Volume, Iasi, 240.
   

BREVET DE INVENTIE

1. Iordachel R., Colt Monica, Bucevschi MD, Iordachel C., Caloianu Maria, Chiriac L., Nicorici Paula, Moldovan Lucia, Compozit bioartificial stratificat pentru regenerare tisulara. Brevet RO 120820/2006.

LUCRARI STIINTIFICE PUBLICATE IN REVISTE DE SPECIALITATE COTATE ISI / INDEXATE IN BAZE DE DATE INTERNATIONALE

1. Craciunescu O., Stefan L., Balan M., Moldovan L., 2007, Evaluation of the radioprotective activity of new green tea-collagen materials, Journal of Optoelectronics and Advanced Materials, 9(8), 2602-2607.
2. Alexandru V., Petrusca D.N., Gille E., Investigation of pro-apoptotic activity of Equisetum arvense L. water extract on human leukemia U 937 cells, Roum. Biotechol. Lett., 12, 2, 3139-3147.
3. Alexandru V., Balan M., Gaspar A., Craciunescu O., Moldovan L., 2007, Studies on the antioxidant activity, phenol and flavonoid contents of some selected Romanian medicinal plants used for wound healing, Roum. Biotechnol. Lett, 12, 6, 3467-3472.
4. Crivoi F., Stefan L., Moldovan L., Vasile C., 2007, Compatibility and cytotoxicity testing of some polyvinyl alcohol and hydrolyzated collagen based blends, Roum. Biotechnol. Lett., 12, 6, 3495-3503.
5. Craciunescu O., Balan M., Gherghina E., Moldovan L., 2007, Influence of polysaccharides from Viscum album L. on human dermal fibroblasts in vitro, Planta Medica, 73(9), p. 900.
6. Alexandru V., Balan M., Gaspar A., Coroiu V., 2007, Antioxidant activity, phenol and flavonoid contents of some selected Romanian medicinal plants, Planta Medica, 73(9), p. 905.
7. Craciunescu O., Moldovan L., Bojin D., Vasile C., Zarnescu O., 2007, ESEM observations on new polyurethane-based materials for biomedical applications: structure and cell adhesion, Acta Microscopica, 16 (1-2, Suppl. 2) p.199-200.
8. Trif M., Moisei M., Chelu F., Moldovan L., Craciunescu O., Roseanu A., 2007, Lipid nanostructures as carriers for targeting pharmacological active agents; formulation and in vitro studies, Proceedings of European and International Forum on Nanotechnology, Dusseldorf, Germany, 80-82.
   

LUCRARI STIINTIFICE PUBLICATE IN ALTE REVISTE DE SPECIALITATE

1. Trif M., Moldovan L., Moisei M., Stefan L., Zarnescu O., 2007, LP-63 Comparative microscopic characterization of free liposomes and liposomes encapsulating chondroitin sulfate and its effect on articular chondrocyte culture, Proceedings of the 8th Multinational Congress on Microscopy, J. Nebesarova, P. Hozak, eds., Prague, Czech Republic, 555-556.
2. Craciunescu O., Zarnescu O., Lungu M., Macocinschi D., Moldovan L., 2007, Natural fiber-coated polyurethane for medical device fabrication, Nanomedicine-Preprints, ed. C. Kiparissides, (International Conference on Nanomedicine, Chalkidiki, Greece), p. 197-203.
3. Craciunescu O., Balan M., Gaspar A., Stefan L., Moldovan L., 2007, Preparation and characterization of porous collagen-agarose sponges for skin repair, Romanian Biological Sciences, V, 1-2, 29-30.
4. Alexandru V., Albisor D., Coroiu V., Craciunescu O., Moldovan L., 2007, Survival and adhesion of fibroblasts seeded on different collagenous materials, Romanian Biological Sciences, V, 1-2, 1-2.
5. Oancea A., Craciunescu O., Balan M., Gaspar A., Oprita I., Moldovan L., 2007, Material compozit cu aplicatii in ingineria tesutului osos, Romanian Biological Sciences, V, nr. 3-4, p.1-8.
   

CARTI

1. Moldovan L., Craciunescu O., Zarnescu O., Popescu M.C., Lungu M., Radu G.L., 2007, “Tehnici actuale si de perspectiva pentru testarea in vitro a biocompatibilitatii biomaterialelor colagenice de uz medical”, in Tehnici Experimentale in bioanaliza (coordonator G.L. Radu), Ed. Printech, vol. V, p. 250-279. (ISBN 978-973-718-856-4)

COMUNICARI LA CONGRESE INTERNATIONALE

1. Minos Brokerage event in new technologies and materials FP7/2007: NMP/ICT - Designing porous bioactive scaffolds based on extracellular matrix components for tissue engineering
2. Minos Brokerage event in new technologies and materials FP7/2007: NMP/ICT - Biological properties improvement of polymeric matrices for medical devices. Biocompatibility analysis of nanostructurated composite materials
3. Mihaela Trif, Lucia Moldovan, Magdalena Moisei, Oana Craciunescu, Otilia Zarnescu, 2007, Effect of empty liposomes and liposomes entrapped chondroitin sulphate on human fibroblasts, The International Conference on Nanoscience and Technology, Beijing, China, Abstract Book, 454-455
4. Craciunescu Oana, Moldovan Lucia, Lungu Maria, Vasile Cornelia, D. Bojin, Zarnescu Otilia, 2007, Natural fiber-coated polyurethane used for medical device fabrication, The International Conference on Nanomedicine, Chalkidiki, Greece, poster
5. Trif M., Moldovan L., Moisei M., Craciunescu O., Chelu F., Roseanu A., Brewer J.M., 2007, Physico-chemical and drug delivery aspects of liposome encapsulated anti-inflammatory biological agents, Nanomedicine-preprints, ed. C. Kiparissides, Chalkidiki, Greece, p. 23.
6. Crivoi F., Moldovan L., Vasile C., 2007, Etude biologique des melanges APV-CH, 8eme Colloque Franco-Roumain sur les Polymeres, Grenoble-France, poster
7. Maria Lungu, Florica Petrescu, Cornelia Vasile, Doina Macocinschi, Lucia Moldovan, Oana Craciunescu, 2007, Natif polymers et polyurethane melanges pour des applications medicales, 8eme Colloque Franco-Roumain sur les Polymeres, Grenoble-France, poster
8. Stefan L., Craciunescu O., Gaspar A., Gherghina E., Moldovan L., 2007, Antiproliferative effect of Helleborus purpurances and Viscum album polysaccharides on human glioblastoma cell line, ELSO 2007, Dresda, Germany, Proceedings, p. 134.
   

COMUNICARI LA CONGRESE NATIONALE

1. M. Chivu, P. Sarbu-Boeti, C. Efrimescu, C. Bleotu, L. Dragomir, L. Moldovan, 2007, Cultivarea celulelor stem mesenchimale in matrici de colagen 3D cu aplicatii in tehnici de inginerie tisulara, Simpozion “Nicolae Cajal”, Academia Romana, 28-29 Martie 2007, Bucuresti.
2. M. Trif, L. Moldovan, M. Moisei, O. Craciunescu, F. Chelu, P. Florian, A. Roseanu, 2007, Lipid nanocapsules as delivery system for pharmacological active agents: formulation and in vitro studies, Al 6-lea Seminar National de Nanostiinta si nanotehnologie, Academia Romana, Academia Romana, 26 Martie 2007, Bucuresti.
3. M. Trif, L. Moldovan, M. Moisei, O. Craciunescu, F. Chelu, P. Florian, A. Roseanu, 2007, Physicochemical and drug delivery aspects of liposome-encapsulated anti-inflammatory drugs, National Conference of Biophysics, Universitatea de Medicina si Farmacie “Carol Davila”, Bucuresti.
4. Moldovan L., Balan M., Gaspar A., Albisor D., Zarnescu O., 2007, Development of collagen and chitosan scaffolds for skin tissue engineering, Workshop “From Basic Science to Therapeutic Applications”, Bucuresti, Book of Abstracts, 58.
5. Stefan L., Gherghina E., Gaspar A., Brehar F., Buzgariu W., 2007, Isolation and characterization of a human glioblastoma cell line, 1st Conference in New Perspectives in Cancer Pathology, 24-27 mai 2007, Bucuresti.
6. Craciunescu O., Moldovan L., Stefan L., Vasile C., Macocinschi D., Miculescu F., Zarnescu O., 2007, Materiale compozite poliuretanice biocompatibilizate pentru uz medical, Simpozionul National de Biomateriale “Biomateriale si Aplicatii Medico-chirurgicale”, Cluj-Napoca, 18-20 oct., p. 53.
7. Oprita I., Craciunescu O., Balan M., Tardei C., Moldovan L., 2007, Material compozit pe baza de colagen si fosfat tricalcic folosit in regenerarea osoasa, Sesiunea Stiintifica Anuala a INCDSB, 14 dec., Bucuresti.
8. Stefan L.M., Craciunescu O., Gaspar A., Gherghina E., Moldovan L., 2007, Efectul antiproliferativ al polizaharidelor extrase din Helleborus purpurascens si Viscum album asupra celulelor umane de glioblastom, Sesiunea Stiintifica Anuala a INCDSB, 14 dec., Bucuresti.
9. Alexandru V., Craciunescu O., Balan M., Leau T., Moldovan L., 2007, Un nou bioprodus utilizat in vindecarea ranilor pielii, Sesiunea Stiintifica Anuala a INCDSB, 14 dec., Bucuresti.
10. Sidoroff M., Moldovan L., Oancea A., Toma L., Stefan L.M., Coroiu V., Gherghina E., 2007, Dezvoltarea unui laborator de testare in vitro a biocompatibilitatii dispozitivelor medicale in concordanta cu normele europene, Sesiunea Stiintifica Anuala a INCDSB, 14 dec., Bucuresti.

CERERE DE BREVET DE INVENTIE

1. Mihaela Trif, Magdalena Moisei, Lucia Moldovan, Oana Craciunescu, Otilia Zarnescu, 2007, “Compozitie farmaceutica pe baza de glicozaminoglicani pentru prevenirea si tratarea afectiunilor cartilajului articular”, Nr. A/00838.

PREMII

2 premii ale Academiei Romane pentru lucrari prezentate la Simpozionul “Nicolae Cajal”, 28-29 Martie 2007, Bucuresti si 1st Conference in New Perspectives in Cancer Pathology, 24-27 mai 2007, Bucuresti.

ANUL 2008

LUCRARI STIINTIFICE PUBLICATE IN REVISTE DE SPECIALITATE cotate ISI / indexate in baze de date internationale

 

 

1. Alexandru V., Balan M., Gaspar A., Craciunescu O., Moldovan L., 2007, Studies on the antioxidant activity, phenol and flavonoid contents of some selected Romanian medicinal plants used for wound healing, Roum. Biotechnol. Lett, 12, 6, 3467-3472.
2. Moldovan L., Craciunescu O., Zarnescu O., Macocinschi D., Bojin D., 2008, Preparation and characterization of new biocompatibilized polymeric materials for medical use, J. Optoelectron. Adv. Mat., 10(4), 942-947
3. Craciunescu O., Lungu M., Zarnescu O., Gaspar A., Moldovan L., 2008, Physico-chemical and biological evaluation of polyurethanic materials covered with natural polymers, Materiale Plastice, 45(2), 163-166
4. Lucia Moldovan, Oana Craciunescu, Mirela Balan, Alexandra Gaspar, Elena Gherghina, 2008, The purification, physico-chemical characterization and bioactivity of polysaccharides from Viscum album, Revista de Chimie, 59, nr. 9, 1022-1025
5. Elena I. Oprita, Lucia Moldovan, Oana Craciunescu, Otilia Zarnescu, 2008, In Vitro behaviour of osteoblast cells seeded into a COL/β-TCP composite scaffold, Central European Journal of Biology, 3(1), 31-37.
6. Trif M., Moldovan L., Moisei M., Craciunescu O., Zarnescu O., 2008, Liposomes entrapped chondroitin sulphate: Ultrastructural characterization and in vitro biocompatibility. Micron, 39, 1042-1045
7. Trif M., Moisei M., Craciunescu O., Zarnescu O., Roseanu A., Moldovan L., 2008, Liposome formulations of chondroitin sulfate: Characterisation and in vitro evaluation of anti-inflammatory activity, European Journal of Clinical Investigation, 38(Suppl. 1), 68-69.
8. Moldovan L., Craciunescu O., Utoiu E., Leau T., Vasile C., Zarnescu O., 2008, In vitro and in vivo testing of biocompatibilized polyurethane materials for medical use, Virchows Archiv, 452 (Suppl 1), p. S238-S239.
9. Craciunescu O., Moldovan L., Oprita E.I., Balan M., Gaspar A., Zarnescu O., 2008, Three-dimensional collagen-chondroitin sulfate-hydroxyapatite composite scaffolds for bone regeneration, Virchows Archiv, 452 (Suppl 1), p. S119.
10. Zarnescu O., Craciunescu O., Balan M., Moldovan L., 2008, Collagen-chondroitin sulfate-hydroxyapatite porous composites: a histochemical approach, Folia Histochemica et Cytobiologica, vol. 46 (suppl. 2), S119, ISSN 0239-8508

LUCRARI STIINTIFICE PUBLICATE IN alte REVISTE DE SPECIALITATE

1. Ch. Tardei, F. Grigore, L. Moldovan, O. Craciunescu, E.I. Oprita, 2008, Preparation and characterization of bioresorbable synthetic scaffolds composed from different beta-tricalcium phosphate powders and collagen, Proc. 2nd International Congress on ceramics – ICC2, 29 iunie-4 iulie, Verona, Italia, pg. 1-7. ISBN 978-88-8080-084-2
2. Ch. Tardei, L. Moldovan, O. Craciunescu, 2008, Hybrid bioresorbable composites with high bioactivity properties, Proceedings of the International conference on ecological materials and technologies, Bucuresti, Ecomat 2008, 23-25 sept, p. 90-94. ISBN 978-606-521-079-0
3. Trif M., Moisei M., Roseanu A., Craciunescu O., Zarnescu O., Moldovan L., 2008, Lipid microstructures as controlled delivery system for bioactive molecules: a novel approach to rheumatic disorders therapy, Proceedings BiomMedD’2008, p. 109-110, ISBN 978-606-521-131-5
4. Leau T., Leau F., Zarnescu O., Lungu M., Utoiu E., 2008, Histological researches regarding tisular reaction after the implant of some polimerics, Lucrari stiintifice, C Series, LIII, p. 291-294.

CARTI/CAPITOLE PUBLICATE

 

Toma Liana, Cap. 2 - Studiul apoptozei prin citometria in flux, in Tehnici Experimentale in Bioanaliza, Vol VI, pp. 28-74, 2008.

 

 

COMUNICARI PREZENTATE LA Conferinte interNATIONALE

 

 

1. Zarnescu O., Moldovan L., Craciunescu O., Leau T., 2008, Tissue response to subcutaneous implantation of collagen-polyurethane composites in rats, 9th International Conference on nanostructured Materials, NANO-2008, 1-6 iunie 2008, Rio de Janeiro, Brazil, Abstracts, p.67.
2. Craciunescu O., Gaspar A., Balan M., Toma L., Stefan L., Moldovan L., 2008, Purification and antiproliferative activity of Helleborus purpurascens polysaccharides, Fifth Conference on Medicinal and Aromatic Plants of Southeast European Countries, Book of Abstracts, p. 157,  Brno, Cehia, 2-5 sept., ISBN: 978-80-375-205-7
3. Zarnescu O., Trif M., Moisei M., Craciunescu O., Moldovan L., 2008, In vitro comparison of biocompatibility of three formulations of liposomes containing chondroitin sulfate, Proceedings of 7 th Annual ELSO Meeting, Nice, Franta, 30 aug-2 sept 2008, p. 202.
4. Zarnescu O, Craciunescu O, Oprita EI, Moldovan L, 2008, Comparative study of in vitro colonization of two porous collagen-chondroitin sulfate-hydroxyapatite composites by rat osteoblasts, Proceedings of 7 th Annual ELSO Meeting, Nice, Franta, 30 aug-2 sept 2008, p. 122.
5. Craciunescu O., Oprita E.I., Moldovan L., Zarnescu O., 2008, Morphological characterization and in vitro evaluation of two porous nano-b-tricalcium phosphate/collagen/chondroitin sulphate composites, 9th International Congress on Cell Biology (ICCB 2008), Seoul, Coreea de Sud, 7-10 octombrie 2008, pag. 499.
6. Craciunescu O., Oprita E.I., Tardei C., Zarnescu O., Moldovan L., 2008, Bioactivity of collagen-nano-beta-tricalcium phosphate crosslinked scaffolds used in bone tissue engineering, Poster presentation-Bone-tec 2008 (International Bone-Tissue-Engineering Congress, 7-9 November, 2008, Hannover, Germany), p. 90.
7. Sidoroff M., Moldovan L., Craciunescu O., Manoiu S., 2008, Development of some biocompatible collagen-chondroitin sulfate-hydroxyapatite composites for tissue regeneration, 9th International Conference on Nanostructured Materials, Rio de Janeiro, Brazil, 1-6 June 2008.
8. E.I. Oprita, V. Alexandru, V. Coroiu, L. Moldovan, 2008, Effect of Equisetum arvense L. on bone cells isolated from newborn rat calvarial bones, 5th CMAPSEEC, 2-9 sept 2008, Brno, Cehia, Book of Abstracts, p. 32, ISBN 978-80-7375-205-7.

COMUNICARI PREZENTATE LA Conferinte NATIONALE

 

1. Craciunescu O., Alexandru V., Moldovan L., 2008, Bioactivity of collagen-catechin crosslinked sponges, Ecomat 2008 - International conference on ecological materials and technologies, Bucuresti, 23-25 sept., p. 22.
2. Craciunescu O., Moldovan L., Oprita E.I., Tardei Ch., Ali S., Tanase A.V., 2008, Structure of nano-beta-tricalcium phosphate/collagen scaffolds and their in vitro bioactivity, BioMedD 2008 – Conference Proceedings, 3rd International Conference on Biomaterials and Medical Devices, Bucharest, 13-16 noiembrie 2008, p. 203, ISBN 978-606-521-131-5.
3. Trif M., Moisei M., Roseanu A., Chelu F., Craciunescu O., Moldovan L., 2008, Effects of lipid nanostructures encapsulating bioactive agents on human articular chondrocytes, Annual International Meeting SRBBM, 29-30 mai 2008, Bucuresti, Romanian Journal of Biochemistry, vol. 45, nr. 1, pg. 124, 2008. - CNCSIS tip C.
4. Oprita E.I., Craciunescu O., Apatean A., Moldovan L., 2008, Potentialul celulelor stem mezenchimale adulte in medicina regenerativa, Sesiunea Stiintifica Anuala a INCDSB, 12 dec. 2008.
5. Craciunescu O., Moldovan L., Oprita E.I., Balan M., Gaspar A., Leau F., Tardei C., 2008, Nano-β-tricalcium phosphate/collagen materials with improved biostability for bone replacement applications, The 4^th edition of International Conference Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies, ATOM-N 2008, 28-31 august 2008, Constanta, Romania, S2-P1, ISBN 978-973-755-387-4.
6. Ch. Tardei, F. Grigore, L. Moldovan, O. Craciunescu, 2008, Sinteza, caracterizarea si evaluarea β-Ca₃(PO₄)₂ , compus majoritar in biocompozitele hibride bioresorbabile, Al 7-lea Simpozion National de Pulberi Ceramice, 8.05.2008, Bucuresti.

CERERI DE BREVETE DE INVENTIE

Moldovan L, Lungu M, Craciunescu O, Materiale biocompatibile obtinute prin acoperirea poliuretanului cu biopolimeri si procedeu de obtinere, Cerere OSIM, Nr. A/00468, 2008.

1. Craciunescu O., Tardei Ch., Moldovan L., 2009, Nano-β-tricalcium phosphate/collagen materials with improved biostability for bone replacement applications, Proceedings SPIE, vol. 7297, 72971B(1-4) (indexed in several databases)
2. Sirbu-Boeti M.P., Chivu M, Paslaru L., Efrimescu C, Herlea V., Pecheanu C., Moldovan L, Dragomir L, Bleotu C, Ciucur E, Vidulescu C, Vasilescu M, Boicea A, Manoiu S, Ionescu MI, Popescu I, 2009, Transplantation of mesenchymal stem cells cultured on biomatrix support induces repairing of digestive tract iatrogenic defects, Chirurgia, 104 (1), 55-65 (SCIE, PubMed indexed)
3. Trif M., Moisei M., Craciunescu O., Zarnescu O., Roseanu A., Moldovan L., 2009, Effects of the glycosaminoglycans-containing liposomes on human articular chondrocytes: evaluation of the therapeutic potential in degenerative disorders, European Journal of Clinical Investigations, 39 (Suppl. 1), 34. (Impact factor 2.784)
4. Oprita E.I., Tardei C., Zarnescu O., Moldovan L., Craciunescu O., 2009, Bioactivity of collagen-nano-beta-tricalcium phosphate crosslinked scaffolds used in bone tissue engineering, Tissue Engineering Part A, 15(5), O-19. (Impact factor 4,699)
5. Moldovan L., Craciunescu O., Oprita E.I., Balan M., Zarnescu O., 2009, Collagen-chondroitin sulfate-hydroxyapatite porous composites: preparation, characterization and in vitro biocompatibility testing, Roumanian Biotechnological Letters, 14(3), 4459-4466 (SCIE indexed)
6. Crivoi F., Stefan L., Moldovan L., Vasile C., 2009, New biocompatible materials by PVA/HC and biological polymers, Journal of Optoelectron Advanced Materials, 11(3), 356-365. (Impact factor 0,433)
7. Raschip I.E., Moldovan L., Stefan L., Oancea A., Vasile C., 2009, Compatibility and cytotoxicity testing of some new biomaterials based on polyurethane and hydroxypropylcellulose blends, Optoelectronics and Advanced Materials - Rapid Communications, 3(12), 1336 –1342 (Impact factor 0,451)
8. Bratu M.M., Roncea F., Moldovan L., Craciunescu O., Negreanu-Pirjol T., Taralunga Gh., 2009, In vitro evaluation of new topical preparation based on polyphenols, zinc and a matrix animal components, Archives of the Balkan Medical Union, 44(1), 31-34 (EMBASE, SCOPUS indexed)
9. Zarnescu, O., Moldovan, L., Craciunescu, O., Trif, M., Moisei, M., 2009, Morphological characterization and in vitro biocompatibility of a collagen-liposomes-entrapped glycosaminoglycans composite, Tissue Engineering and Regenerative Medicine, 6 (12), S118 (EMBASE, SCOPUS indexed)


1. Gaspar A., Apatean A., Craciunescu O., Moldovan L., 2009, Flavonoids incorporated in collagen matrices for tissue engineering, Romanian Biological Sciences, VII(1-4), 43-48.
2. Balan M., Toma L., Moldovan L., Deliu C., Oniga I., 2009, In vitro cytotoxicity and caspase activation assessment of Hypericum perforatum and Hypericum maculatum, Romanian Biological Sciences, VII(1-4), 15-22.
3. Utoiu E., Coroiu V., Lungu M., Oancea A., Moldovan L., 2009, Assessment of the matrix metalloproteinase induced in hypodermic tissue by implantation of biopolimeric films, Romanian Biological Sciences, VII(1-4), 129-138.
4. Florescu I.P., Mihai R., Moldovan L., 2009, A documentary study regarding the use of nervous conduits in nerve regeneration, Annals of plastic surgery and reconstructive microsurgery, nr. 4


1. Toma Liana, Radu G.L., 2009, Microscopia holografica digitala, aplicatii in biologie, Tehnici Experimentale in Bioanaliza, p. 1-29, Ed. Printech, ISBN 978-606-521-439-2.
2. Oprita E.I., Radu G.L., 2009, Analiza potentialului celulelor stem mezenchimale in medicina regenerativa, Tehnici Experimentale in Bioanaliza, p. 30-54, Ed. Printech, ISBN 978-606-521-439-2.


1. Zarnescu O., Moldovan, L., Craciunescu, O., Trif, M., Moisei, M., 2009, Preparation, morphological characterization and in vitro biocompatibility of a collagen-liposomes-entrapped chondroitin sulphate composites, International Conference on Materials for Advanced Technologies ICMAT, p.18-19, 28 iunie-3 iulie, Singapore.
2. Tardei Ch., Craciunescu O., Balan M., Stoleriu S., Trusca R., Vasile E., 2009, Synthesis, characterization and the solubility of beta-TCP powders with Mg and Zn based dopants, Poster presentation P.S.E.4. at 11th Annual Conference YUCOMAT 2009, 31 aug – 4 sept, Herceg-Novi.
3. Trif, M., Moisei, M., Craciunescu, O., Zarnescu, O., Roseanu, A., Moldovan, L., 2009, Liposomes based glycosaminoglicans, evaluation of the therapeutic potential in osteoarthritis, Romanian Journal of Biochemistry, 46, Suppl., 122-123 (CNCSIS C), Annual International Meeting of SRBBM, 30 sept-3 oct, Cluj-Napoca.
4. Zarnescu O., Moldovan L., Craciunescu O., Trif M., Moisei M., 2009, Morphological characterization and in vitro biocompatibility of a collagen-liposomes-entrapped glycosaminoglycans composite, Tissue Engineering and Regenerative Medicine, 6(12), S118, 2nd World Congress Tissue Engineering & Regenerative Medicine International Society, 31 august - 3 septembrie, Seoul, Coreea de Sud.
5. Zarnescu O., Craciunescu O., Oprita E.I., Moldovan L., 2009, A comparative study of morphology and in vitro biocompatibility of two types of porous bioceramics for bone graft applications: nano-tricalcium phosphate/collagen and hydroxyapatite/ collagen composites, Tissue Engineering and Regenerative Medicine, 6 (12), S245, 2nd World Congress Tissue Engineering & Regenerative Medicine International Society, 31 august - 3 septembrie, Seoul, Coreea de Sud.


1. Lucia Moldovan, Valentina Alexandru, Oana Craciunescu, Veronica Lazar, Carmen Balotescu, 2009, Hydrogel made of natural components for the regeneration of damaged dermic tissue, Patent RO122181B1/2009


Contract Nr. 582 din 24.02.2009 – S.C. Doctor Natura SRL – Realizarea unor analize ale produsului BIOCELL-10 – concentrat din suc de grau
Comanda 846 si 847 din 31.03.2009 – Institutul de Chimie Macromoleculara Petru Poni Iasi – Efectuari testari citotoxicitate
Comanda 845 din 31.03.2009 – Dumitrescu Dumitru – Analize extract fitoproteic
Comanda 517 din 7.05.2009 – IFIN HH BIOEVAL – Intercomparare testarea citotoxicitatii
Comanda 226 din 7.05.2009 – UPB – Centrul de cercetari si expertizari metalurgice ECOMET – Teste de biocompatibilitate pe probe de aliaj metalic Ti6Al-4W
Comanda 316 din 7.12.2009 – SC Denticare Implantology Center SRL – Teste de biocompatibilitate pe folie polimerica presata



1. Mihele D., Moldovan L., Mihele D., Darmanescu D., Georgescu S.R., 2010, Determination on cell cultures of the proliferative action of some semisolid preparations for topical use with Amygdali oleum, Farmacia, 58(1), 102-107 (Impact factor 0,064)
2. Zarnescu O., Craciunescu O., Moldovan L., 2010, Collagen-chondroitin sulphate-hydroxyapatite porous composites: a histochemical and electron microscopy approach, Microscopy and microanalysis, 16, 137-142 (Impact factor 2,992)
3. Craciunescu O., Moldovan L., Tardei Ch., 2010, Bioactivity of cross-linked nano-beta-tricalcium phosphate/collagen materials designed for bone tissue regeneration, Materiale Plastice, 47(1), 59-63 (Impact Factor 0.873)
4. Tardei Ch., Moldovan L., Craciunescu O., 2010, Hybrid bioresorbable composites with high bioactivity properties, Romanian Journal of Materials, 40(1), 41-49 (Impact factor 0,242)
5. Stancu E.C., Ionita M.D., Vizireanu S., Stanciuc A.M., Moldovan L., Dinescu G., 2010, Wettability properties of carbon nanowalls layers deposited by a radiofrequency plasma beam discharge, Materials Science and Engineering B-Advanced Functional Solid-State Materials, 169 (1-3), 119-122 (Impact factor 1,577)
6. Popescu M.C., Vasile C., Craciunescu O., 2010, Structural analysis of some soluble elastins by means of FT-IR and 2D IR correlation spectroscopy, Biopolymers, 93(12), 1072-1084 (Impact factor 2,605)
7. Popescu M.C., Vasile C., Macocinschi D., Lungu M., Craciunescu O., 2010, Biomaterials based on new polyurethane and hydrolyzed collagen, k-elastin, hyaluronic acid and chondroitin sulfate, International Journal of Biological Macromolecules, 47(5), 646-653 (Impact factor 2,366)
8. Lungu M., Moldovan L., Craciunescu O., Doicin C., 2010, Biocompatible Blends Based on Polyvinyl Chloride and Natural Polymers for Medical Device Fabrication, Materiale Plastice, 47(3), 278-281 (SCIE indexed)
9. Lucarelli E., Beretta R., Dozza B., Tazzari P.L., O’Connell S.M., Ricci F., Pierini M., Squarzoni S., Pagliaro P.P., Oprita E.I., Donati D., 2010, A Recently Developed Bifacial Platelet-Rich Fibrin Matrix, European Cells and Materials, 10, 13-23 (Impact factor 9,650)
10. Toma L., Constantin D., 2010, A flow cytometric comparison of two glioblastoma cell lines, Banat’s Journal of Biotechnology, 2, 43-47 (indexata ProQuest).


1. Vasile Sorin Mănoiu, Angel Aloman, 2010, Obtaining nanoparticles by electrolytic method, U.P.B. Sci. Bull., Series B, 72(1), 157-166
2. Vasile Sorin Mănoiu, Angel Aloman, 2010, Obtaining silver nanoparticles by sonochemical methods, U.P.B. Sci. Bull., Series B, 72(2), 179-186


1. Trif M., Moisei M., Craciunescu O., Chelu F., Zarnescu O., Roseanu A., Moldovan L., 2010, Lipid-based Nanoparticles as Carriers for Intracellular Drug Delivery in Nanostructuring and nanocharacterization, series in Micro and Nanoengineering (Coordonatori: M. Zaharescu, Ciurea M., Kleps I., Dascalu D.), Editura Academiei Romane, vol. 16, p. 257-271, ISBN 978-973-27-1905-3


1. Craciunescu O., Tardei Ch., Oprita E.I., Moldovan L., Zarnescu O., 2010, Osteoblast responses to magnesium-substituted nano-tricalcium phosphate – collagen porous scaffold, TERMIS-EU Meeting 2010, ISBN 978-0-9564492-0-7, Galway, Ireland, 13-17 June 2010.
2. Zarnescu O., Craciunescu O., Oprita E.I., Moldovan L., 2010, In vitro cellular responses of TCP-collagen composites cross linked with EDC, TERMIS-EU Meeting 2010, ISBN 978-0-9564492-0-7, Galway, Ireland, 13-17 June 2010.
3. Zarnescu O., Moldovan L., Trif M., Moisei M., Craciunescu O., 2010, Light and electron microscopy characterization of a collagen-liposomes-entrapped chondroitin sulphate composite as intra-articular drug delivery system, Abstract Book Symposium on Innovative Polymers for Controlled Delivery, ISBN 978-7-81137-581-7, J. Feijen & Z. Zhong, eds., pp. 288-290, 14-17 sept 2010, Suzhou, China,
4. Trif M., Moldovan L., Moisei M., Chelu F., Craciunescu O., Mattsby-Baltzer I., Roseanu A., 2010, Lipid nanostructures as drug delivery system for pharmacological active agents; formulation and in vitro studies, Abstract Addendum, E1.35, p. 26, 35th FEBS Congress Molecules of Life, 26 iun-1 iul 2010, Gothenburg, Suedia
5. Stancu E.C., Stanciuc A.M., Acsente T., Mitu B., Moldovan L., Dinescu G., 2010, Selective growth of cells on various carbon material surfaces, The European Materials Research Society (E-MRS 2010), Strasbourg, France, June 7-11


1. Trif M., Moisei M., Roseanu A., Zarnescu O., Maris D., Maris M., Craciunescu O., Moldovan L., 2010, Lipid vesicles for effective delivery of anti-inflammatory molecules: development, characterization and performance evaluation, Romanian Journal of Biochemistry, 47, Suppl., 26-27, (CNCSIS B), The Annual International Conference of the Romanian Society of Biochemistry and Molecular Biology, 23-25 sept. 2010
2. Stancu E.C., Stanciuc A.M., Ionita M.D., Teodorescu M., Moldovan L., Dinescu G., 2010, Micropatterned polymeric surfaces preparation by atmospheric pressure plasma for interactions with cells, The 15th Conference on Plasma Physics and Applications (CPPA 2010), 1-4 iulie, Iasi, Romania.
3. Balan M., Craciunescu O., Gaspar A., Moldovan L., 2010, Studii privind utilizarea unor materiale compozite in ingineria tisulara osoasa, Sesiunea Stiintifica Anuala INCDSB, 24-25 iunie 2010, Cluj-Napoca – comunicare orala



1. Mihaela Trif, Magdalena Moisei, Lucia Moldovan, Oana Craciunescu, Otilia Zarnescu, 28.05.2010, Compozitie farmaceutica pe baza de glicozaminoglicani pentru prevenirea si tratarea afectiunilor cartilajului articular si procedeu de obtinere a acesteia, Patent RO 122949 B1.
2. Moldovan L, Lungu M, Craciunescu O, 2010, Material biocompatibil stratificat pe baza de poliuretan si polimeri naturali si procedeu de preparare a acestuia, Patent RO 123117 B1 – Premiat la Bruxelles INNOVA-2010 cu medalia de argint


Comenzi de testare a citotoxicitatii dispozitivelor medicale pentru:
- SC Dentalcare SA
- SC Greenfieber SA
- CE MARK SRL



1. Moldovan L., Gaspar A., Toma L., Craciunescu O., Saviuc C., 2011, Comparison of polyphenolic content and antioxidant capacity of five Romanian traditional medicinal plants, Revista de Chimie, 62(3), 299-303 (Impact factor 0,552)
2. Craciunescu O., Tardei Ch., Moldovan L., Zarnescu O., 2011, Magnesium substitution effect on porous scaffolds for bone repairing, Central European Journal of Biology, 6, 301-311 (Impact factor 0,915)
3. Gaspar A, Moldovan L., Constantin D., Stanciuc A.M., Sarbu-Boeti M.P., Efrimescu I.C., 2011, Collagen-based scaffolds for skin tissue engineering, Journal of Medicine and Life, IV (2), 172-177 (PubMed indexed)
4. Stanciuc A.M., Gaspar A., Moldovan L., Saviuc C., Popa M., Marutescu L., 2011, In vitro antimicrobial activity of Romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells, Romanian Archives of Microbiology and Immunology, 70(1),11-14. (Medline/PubMed indexed)
5. Utoiu E., Lungu M., Coroiu V., Oancea A., 2011, Collagen use in biocompatibility enhance of polyethylene glycol, Banat’s Journal of Biotechnology, 3, 50-55 (indexata ProQuest)
6. Mihai R., Florescu I.P., Coroiu V., Oancea A., Lungu M., 2011, In vitro biocompatibility testing of some synthetic polymers used for the achievement of nervous conduits, Journal of Medicine and Life, IV, 3, (PubMed indexed)
7. Rusu M.C., Pop F., Hostiuc S., Dermengiu D., Lala A.I., Ion D.A., Manoiu S., Mirancea N., 2011, The human trigeminal ganglion: c-kit positive neurons and interstitial cells, Annals of Anatomy, 193(5), 403-411 (Impact factor 1,649)
8. Rusu M.C., Jianu A.M., Mirancea N., Didilescu A.C., Mănoiu V.S., Păduraru D., 2011, Tracheal telocytes, Journal of Cellular and Molecular Medicine, doi: 10.1111/j.1582-4934.2011.01465.x. (Impact factor 4,608)


1. Craciunescu O., Moldovan L., Oprita E.I., Gaspar A., Utoiu E., 2011, Cross-linked collagenous matrices for medical applications, Romanian Biological Sciences, IX(1-4), 25-26
2. Gaspar A., Toma L., Craciunescu O., Moldovan L., 2011, Evaluation of in vitro antioxidant properties of some medicinal plants growing in Romania, Romanian Biological Sciences, IX(1-4), 27-28


1. Craciunescu O., Moldovan L., 2011, Cap. 13 - Designing bio-inspired composite materials for medical applications in Nanocomposites and Polymers with Analytical Methods, John Cuppoletti (ed.), InTech, Viena, Austria, pp. 309-334, ISBN: 978-953-307-352-1 (open-access volume) http://www.intechopen.com/articles/show/title/designing-bio-inspired-composite-materials-for-medical-applications
2. Dinescu G., Stancu E.C., Ionita E.R., Teodorescu M., Ionita M.D., Stanciuc A.M., Moldovan L., 2011, Cold expanding plasma sources for processing of biomaterials surfaces, in Biomaterials and plasma processing (ed. by N. Dumitrascu & I. Topala), Ed. Univ AI Cuza Iasi, ISBN: 978-973-703-543-1



1. Zarnescu O., Moldovan L., Trif M., Moisei M., Gaspar A., Craciunescu O., 2011, Light and electron microscopy characterization of a new composite: collagen and Arnica derived polysaccharide-coated liposomes, Histology and histopathology, Cellular and molecular biology, 26(Suppl. 1), p. 57, TERMIS-EU 2011 Annual Meeting, 7-10 iunie 2011, Granada, Spania (Impact Factor 2.404)
2. Moldovan L., Craciunescu O., Toma L., Gaspar A., Constantin D., 2011, Antioxidant potential of Arnica montana and Urtica dioica hydroalcoholic extracts on mouse fibroblasts in vitro, Planta Medica, 77, p. 1316, 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 4-9 sept., Antalya, Turcia (Impact Factor 2,369)
3. Craciunescu O., Gaspar A., Moldovan L., 2011, Role of polyphenolic compounds on biological activity of collagenous materials, Planta Medica, 77, p. 1418, 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 4-9 sept., Antalya, Turcia (Impact Factor 2,369)
4. Alexandru V., Necula R., Ghita G., Gaspar A., Toma A., Tatia R., Gille E., 2011, Evaluation of four traditional Romanian medicinal plants as wound healing agents, Planta Medica, 77, p. 1317, 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 4-9 sept., Antalya, Turcia (Impact Factor 2,369)
5. Zarnescu O., Mihai A., Utoiu E., Moldovan L., Florescu I.P., 2011, Histological and immunohistochemical evaluation of rat sciatic nerve regeneration after application of collagen-polyvinyl alcohol scaffold, Virchows Archives, 459 (Suppl 1), S273-S274, 23rd European Congress of Pathology, 27 aug-1 sept 2011, Helsinki, Finland (Impact Factor 2,336)
6. Moisei M., Zarnescu O., Roseanu A., Moldovan L., Craciunescu O., Trif M., 2011, Development and characterization of lipid vesicles for effective delivery of anti-inflammatory molecules, EuroNanoForum, 30 mai-1 iunie 2011, Budapest, Ungaria
7. Trif M., Moisei M., Roseanu A., Utoiu E., Moldovan L., 2011, Lipid nanostructure based chondroitin sulphate. Evaluation of biocompatibility and efficiency in local therapy of osteoarthritis, EuroNanoForum, 30 mai-1 iunie 2011, Budapest, Ungaria
8. Trif M, Moisei M, Roseanu A, Utoiu E, Craciunescu O, Moldovan L, 2011, Evaluation of biocompatibility and therapeutic potential of lipid nanostructure based chondroitin sulphate on in vitro model of inflammatory arthritis, Romanian Journal of Biochemistry, 48, Suppl., P.1-92, The Annual International Conference of the Romanian Society of Biochemistry and Molecular Biology & The Conference on Cellular and Molecular Biotechnologies on Medical Application, 28-30 September, 2011, Craiova, Romania
9. Zarnescu O., Moldovan L., Trif M., Moisei M., Gaspar A., Leau F., 2011, Porous scaffold made from collagen and liposomes coated with plant derived polysaccharide – in vivo study, Abstracts CD, International Materials Research Congress, IMRC XX, Mexic
10. D. Batalu, D. Bojin, G. Aldica, A. Stanciuc, L. Moldovan, M. Bucur, P. Badica, 2011, Evaluation of MgB2-based Nano-Composites for Medical Applications, 24th European Conference on Biomaterials, The Annual Conference of the European Society for Biomaterials, 4-8 September 2011, Book of Abstracts, p. 67.


1. Lungu M, Moldovan L, Craciunescu O, Zarnescu O, Vasile C, 2011, Compozitie de material biocompatibil si procedeu de obtinere a acesteia, Patent RO 123177 B1 din 28.01.2011
2. Craciunescu O., Moldovan L., Tardei Ch., Oprita E.I., Zarnescu O., 2010, Suport compozit poros pentru tratarea defectelor osoase si procedeu de obtinere, Nr. cerere de brevet A/00567 din 30.06.2010
3. Moldovan L., Craciunescu O., Trif M., Zarnescu O., Moisei M., Gaspar A., 2011, Material biocompatibil poros cu rol in stimularea regenerarii cartilajului si procedeu de obtinere, Nr. cerere brevet A/00910 din 16.09.2011
4. Valentina Alexandru, Gille Elvira, Necula Radu, Leau Florin, Savin Simona, Tatia Rodica, 2011, Preparat topic peliculogen cu efect protector, regenerativ si cicatrizant, Nr. cerere brevet A/00876 din 09.2011
5. Sarbu-Boeti MP, Manof AI, Efrimescu CI, Moldovan L, Bleotu C, Chivu M, Paslaru LL, Dima SO, Fota R, Ionescu MI, Tanase A, Herlea V, Vasilescu M, Ciucur E, Popescu I, Dispozitiv multifunctional de evaluare pentru obtinerea unui pansament biocelular si structuri tisulare regenerate, Nr. cerere brevet A/01204/2010/12.05.2011
6. Florescu I., Mihai R., Lungu M., Moldovan L., Zarnescu O., Coroiu V., Utoiu E., Stanciuc AM., 2011, Biocompozit pe baza de alcool polivinilic si colagen pentru obtinerea de conducte nervoase si procedeu de obtinere, Nr. cerere brevet A/01241/25.11.2011


Comenzi de testare a citotoxicitatii dispozitivelor medicale pentru:
- SC HOFIGAL SA
- UMF Iasi, Facultatea de Bioinginerie Medicala
- CE MARK SRL
- INCDIE ICPE-CA
- INCD pentru Textile si Pielarie
- IFIN HH BIOEVAL